Biologics

Services for Biologics:

covers the characterisation of antibodies or antibody-drug-conjugates:

• Molecular weight determination (intact)
• Determination of drug antibody ratio (DAR)
• Glycan and PTMs analysis
• Extraction of (Fab)2 fragments
• Chain analysis, reduced mass determination
• Proteinogenic impurities

• Peptide Mapping (I-IV)

  I. AA Sequence
  II. Identification of N- and C-Termini
  III. Stress studies (Oxidation, Deamination)
  IV. S-S bridges determination